Hair loss Diagnosis and treatment
Table Of Content
You should regularly check your blood pressure while taking spironolactone, as this can be dangerous if you don’t have high blood pressure. The included studies have variable study designs such as prospective, retrospective, survey study, RCT, and a large case series. The number of patients ranged from 19 to 115, and the age ranged from 12 to 88 years in the included studies.
Treatments for Alopecia and Hair Loss
Spironolactone does not up risk of breast cancer recurrence Latest news for Doctors, Nurses and Pharmacists ... - MIMS
Spironolactone does not up risk of breast cancer recurrence Latest news for Doctors, Nurses and Pharmacists ....
Posted: Wed, 30 Sep 2020 07:00:00 GMT [source]
This variation in hair loss could be the result of locally increased levels of estradiol or decreased levels of testosterone and DHT that is secondary to greater amounts of conversion. A previous systematic review reported that spironolactone was effective in reducing hair loss in women with androgenetic alopecia [16]. In previous research conducted by Burns [14] and Sinclair [13], the efficacy of spironolactone in treating androgenetic alopecia was found to be significantly better with a 12-month treatment compared to a 6-month treatment.
Serious side effects
Spironolactone is an oral form of medication that was initially developed to treat mild blood pressure irregularities and water retention. “Structurally, its backbone is a basic steroidal nucleus with four rings. The primary metabolite of spironolactone is canrenone, which is an active metabolite that is also an antagonist of aldosterone, and thus promotes diuresis,” Gonzalez explains. Spironolactone is a medication usually used for fluid retention but sometimes used to treat a specific type of hair loss. You will need to consult a medical provider to know exactly what is causing your hair loss, and they can then determine the right treatment for that condition.
Nanoxidil for Hair Loss: Efficacy, Side-Effects, Comparison vs. Minoxidil
Here, dermatologists share what you need to know about alopecia, including possible causes, treatment options and what you can do to prevent more hair loss. How often you take spironolactone depends on the condition you’re taking the drug to treat. Studies have determined the dosages that help keep an effective level of the drug in the body for the different conditions spironolactone treats. Your doctor will recommend the right dosage of spironolactone for your condition. Topical spironolactone can be considered a low-risk adjunctive therapy in both men and women.
Spironolactone Side Effects (as a Hair Loss Treatment)
That includes nutritional supplements (especially potassium) and diuretics. Depending on your results, they might increase your dosage or prescribe a different medication to take with or instead of spironolactone. Spironolactone takes a while to start working for hair loss, so don’t be discouraged if you don’t see improvement right away. Always disclose other medications you are on to your healthcare provider.
If your hair loss is caused by an underlying disease, treatment for that disease will be necessary. If a certain medication is causing the hair loss, your doctor may advise you to stop using it for a few months. We offer treatments like Follicular Unit Extraction (FUE) and Follicular Unit Transplant (FUT), where individual hair follicles or strips of scalp are transplanted to balding areas. These methods provide permanent and natural-looking results, making them a top consideration for those seeking comprehensive solutions. Using Spironolactone and Finasteride can result in a harmonious combination therapy that further reduces DHT in the scalp, therefore helping to prevent and reverse hair loss. Recently, there’s been a surge in interest surrounding topical variants of Spironolactone, which are FDA-approved but still in the research and development phase.
Clinical trials
Try to find ways to manage stress, and strive for a well-balanced diet that includes plenty of fruits and vegetables. If you have alopecia, you can help hold onto your tresses by avoiding behaviors that are known to contribute to temporary and permanent hair loss, Mirmirani says. “As soon as you notice hair loss is happening, you should come in,” says Lauren Eckert Ploch, a dermatologist in Aiken, South Carolina.
Geriatric and pediatric patients will also need a case-by-case analysis of whether they can use spironolactone. To avoid experiencing any of these symptoms, you should follow your doctor’s advice when it comes to how much spironolactone you should take and how often. However, certain women are not advised to take it, including those who are pregnant or breastfeeding.
Why Can’t Men Use Spironolactone for Hair Growth?
Burns11 and Sinclair15 compared the efficacy of spironolactone duration at 12 and 6 months, and both reported a greater improvement in the former than the latter. Our systematic review and meta-analysis of available evidence aimed to evaluate the efficacy and safety of oral spironolactone for treating hair loss. The results of this study suggest that oral spironolactone may be an effective treatment for hair loss, especially when combined with other therapies. However, the significant heterogeneity observed in the efficacy outcomes indicates that the treatment response may vary across individuals.
It can also cause loss of libido and sexual dysfunction in males, even causing a decrease in fertility and sperm count. There are other much more effective and FDA-approved options available like finasteride or dutasteride. Spironolactone is an aldosterone receptor antagonist, traditionally used as a ‘diuretic’, which helps to reduce the excess water in the body. It is FDA-approved for the treatment of fluid retention and is also used to treat patients with heart failure and high blood pressure.
It showed better efficacy in combination with other therapies such as oral or topical minoxidil compared with monotherapy. Spironolactone is an effective treatment for hair loss due to androgenic alopecia in women. If you’re interested in trying spironolactone for hair loss, talk to your doctor. Make sure to tell them about any medical conditions you have and the kinds of hair loss treatments you’ve tried in the past.
Over time, this leads to a phenomenon called “follicular miniaturization.” The hair follicles start to shrink, and the hair growth cycle is shortened. As a consequence, hair shafts become finer and shorter, and eventually, the follicles stop producing hair altogether. Pattern hair loss, a concern that affects millions of men and women worldwide, is primarily due to a combination of genetic and hormonal factors.
Every article on Health Guide goes through rigorous fact-checking by our team of medical reviewers. Our reviewers are trained medical professionals who ensure each article contains the most up-to-date information, and that medical details have been correctly interpreted by the writer. Spironolactone is only approved in women because of undesirable side effects that it can have in men (like gynecomastia, or enlarging of breast tissue) (Patibandla, 2021). This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.
This drug may be taken as part of a combination therapy with other medications. This anti-androgen property of spironolactone has also been used in the treatment of hormonal acne and hirsutism. More severe side effects are also possible, including paralysis, numbness, decreased urination, muscle pain and others.
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